A Novel Insight into the Immune-Related Interaction of Inflammatory Cytokines in Benign Prostatic Hyperplasia

Author:

Naiyila Xiaokaiti12,Li Jinze12,Huang Yin12,Chen Bo12,Zhu Mengli3,Li Jin12,Chen Zeyu12,Yang Lu1,Ai Jianzhong1ORCID,Wei Qiang1,Liu Liangren1,Cao Dehong1

Affiliation:

1. Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China

2. West China School of Medicine, Sichuan University, Chengdu 610041, China

3. Research Core Facility, West China Hospital, Sichuan University, Chengdu 610041, China

Abstract

Benign prostatic hyperplasia (BPH) is a common male condition that impacts many men’s quality of life by generating lower urinary tract symptoms (LUTS). In recent years, inflammation has become very common in the prostate, and BPH with inflammation has a higher International Prostate Symptom Score (IPSS) score and an enlarged prostate. Chronic inflammation leads to tissue damage and the release of pro-inflammatory cytokines, which play an important role in the pathogenesis of BPH. We will focus on current advancements in pro-inflammatory cytokines in BPH, as well as the future of pro-inflammatory cytokine research.

Funder

the National Natural Science Foundation of China

Publisher

MDPI AG

Subject

General Medicine

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