Design and Simulation of a Ring Transducer Array for Ultrasound Retinal Stimulation

Author:

Xu Chenlin,Lu GengxiORCID,Kang Haochen,Humayun Mark S.,Zhou Qifa

Abstract

Argus II retinal prosthesis is the US Food and Drug Administration (FDA) approved medical device intended to restore sight to a patient’s blind secondary to retinal degeneration (i.e., retinitis pigmentosa). However, Argus II and most reported retinal prostheses require invasive surgery to implant electrodes in the eye. Recent studies have shown that focused ultrasound can be developed into a non-invasive retinal prosthesis technology. Ultrasound energy focused on retinal neurons can trigger the activities of retinal neurons with high spatial-temporal resolution. This paper introduces a novel design and simulation of a ring array transducer that could be used as non-invasive ultrasonic retinal stimulation. The array transducer is designed in the shape of a racing ring with a hemisphere surface that mimics a contact lens to acoustically couple with the eye via the tear film and directs the ultrasound to avoid the high acoustic absorption from the crystalline lens. We will describe the design methods and simulation of the two-dimensional pattern stimulation. Finally, compared with other existing retinal prostheses, we show that the ultrasound ring array is practical and safe and could be potentially used as a non-invasive retinal prosthesis.

Funder

National Institutes of Health

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Mechanical Engineering,Control and Systems Engineering

Reference49 articles.

1. Foundations of Vision;Wandell,1995

2. Mutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophy

3. Retinitis pigmentosa

4. Retinitis pigmentosa. The Friedenwald Lecture;Berson;Investig. Ophthalmol. Vis. Sci.,1993

5. The Five-year Incidence and Progression of Age-related Maculopathy

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