The Application of Porous Scaffolds for Cardiovascular Tissues

Author:

Watanabe Tatsuya1,Sassi Salha1,Ulziibayar Anudari1ORCID,Hama Rikako1,Kitsuka Takahiro1,Shinoka Toshiharu123ORCID

Affiliation:

1. Center for Regenerative Medicine, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH 43205, USA

2. Department of Surgery, Nationwide Children’s Hospital, Ohio State University, Columbus, OH 43205, USA

3. Department of Cardiothoracic Surgery, The Heart Center, Nationwide Children’s Hospital, Columbus, OH 43205, USA

Abstract

As the number of arteriosclerotic diseases continues to increase, much improvement is still needed with treatments for cardiovascular diseases. This is mainly due to the limitations of currently existing treatment options, including the limited number of donor organs available or the long-term durability of the artificial organs. Therefore, tissue engineering has attracted significant attention as a tissue regeneration therapy in this area. Porous scaffolds are one of the effective methods for tissue engineering. However, it could be better, and its effectiveness varies depending on the tissue application. This paper will address the challenges presented by various materials and their combinations. We will also describe some of the latest methods for tissue engineering.

Publisher

MDPI AG

Subject

Bioengineering

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