The Progression in Developing Genomic Resources for Crop Improvement

Author:

Ruperao Pradeep1ORCID,Rangan Parimalan2ORCID,Shah Trushar3ORCID,Thakur Vivek4,Kalia Sanjay5,Mayes Sean1ORCID,Rathore Abhishek6

Affiliation:

1. Center of Excellence in Genomics and Systems Biology, International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Hyderabad 502324, India

2. ICAR-National Bureau of Plant Genetic Resources, PUSA Campus, New Delhi 110012, India

3. International Institute of Tropical Agriculture (IITA), Nairobi 30709-00100, Kenya

4. Department of Systems & Computational Biology, School of Life Sciences, University of Hyderabad, Hyderabad 500046, India

5. Department of Biotechnology, Ministry of Science and Technology, Government of India, New Delhi 110003, India

6. Excellence in Breeding, International Maize and Wheat Improvement Center (CIMMYT), Hyderabad 502324, India

Abstract

Sequencing technologies have rapidly evolved over the past two decades, and new technologies are being continually developed and commercialized. The emerging sequencing technologies target generating more data with fewer inputs and at lower costs. This has also translated to an increase in the number and type of corresponding applications in genomics besides enhanced computational capacities (both hardware and software). Alongside the evolving DNA sequencing landscape, bioinformatics research teams have also evolved to accommodate the increasingly demanding techniques used to combine and interpret data, leading to many researchers moving from the lab to the computer. The rich history of DNA sequencing has paved the way for new insights and the development of new analysis methods. Understanding and learning from past technologies can help with the progress of future applications. This review focuses on the evolution of sequencing technologies, their significant enabling role in generating plant genome assemblies and downstream applications, and the parallel development of bioinformatics tools and skills, filling the gap in data analysis techniques.

Funder

AVISA

ICAR-BMGF

Department of Biotechnology, Government of India

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference241 articles.

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5. Toward the Sequence-Based Breeding in Legumes in the Post-Genome Sequencing Era;Varshney;Theor. Appl. Genet.,2019

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