Chronic Heart Failure in Children: State of the Art and New Perspectives

Author:

Castaldi Biagio1ORCID,Cuppini Elena1,Fumanelli Jennifer1,Di Candia Angela12ORCID,Sabatino Jolanda12ORCID,Sirico Domenico1ORCID,Vida Vladimiro3ORCID,Padalino Massimo23ORCID,Di Salvo Giovanni12ORCID

Affiliation:

1. Pediatric Cardiology Unit, Department of Women’s and Children’s Health, University of Padua, 35122 Padova, Italy

2. Pediatric Research Institute (IRP) Città della Speranza, University of Padua, 35122 Padova, Italy

3. Pediatric Cardiac Surgery Unit, Department of Cardio Thoracic Sciences, University of Padua, 35122 Padova, Italy

Abstract

Pediatric heart failure (HF) is an important clinical condition with high morbidity and mortality. Compared to adults, pediatric HF shows different etiologies characterized by different physiology, a different clinical course, and deeply different therapeutic approaches. In the last few years, new drugs have been developed and new therapeutic strategies have been proposed with the goal of identifying an individualized treatment regimen. The aim of this article is to review the new potential drugs and non-pharmacological therapies for pediatric heart failure in children.

Publisher

MDPI AG

Subject

General Medicine

Reference57 articles.

1. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines;Heidenreich;Circulation,2022

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3. The International Society for Heart and Lung Transplantation Guidelines for the management of pediatric heart failure: Executive summary;Kirk;J. Heart Lung Transplant.,2014

4. Presentation, diagnosis, and medical management of heart failure in children: Canadian Cardiovascular Society guidelines;Kantor;Can. J. Cardiol.,2013

5. The registry of the international society for heart and lung transplantation: Sixth official pediatric report—2003;Boucek;J. Heart Lung Transplant.,2003

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