Epigenetic Regulation of Optic Nerve Development, Protection, and Repair

Author:

Ashok AjayORCID,Pooranawattanakul Sarita,Tai Wai Lydia,Cho Kin-SangORCID,Utheim Tor P.,Cestari Dean M.,Chen Dong FengORCID

Abstract

Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types of epigenetic regulators and their associated molecular apparatus that affect the optic nerve. A comprehensive understanding of epigenetic regulation in optic nerve development and homeostasis will help us unravel novel molecular pathways and pave the way to design blueprints for effective therapeutics to address optic nerve protection, repair, and regeneration.

Funder

National Eye Institute

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Electrical stimulation alters DNA methylation and promotes neurite outgrowth;Journal of Cellular Biochemistry;2023-08-29

2. The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons;Advanced Science;2023-08-10

3. Optic Neuropathies: Current and Future Strategies for Optic Nerve Protection and Repair;International Journal of Molecular Sciences;2023-04-10

4. Aging Effects on Optic Nerve Neurodegeneration;International Journal of Molecular Sciences;2023-01-29

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