Techniques and Technologies to Improve Vein Graft Patency in Coronary Surgery

Author:

Gemelli Marco1ORCID,Addonizio Mariangela1,Geatti Veronica1,Gallo Michele2ORCID,Dixon Lauren K.3,Slaughter Mark S.2,Gerosa Gino1ORCID

Affiliation:

1. Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35128 Padova, Italy

2. Department of Cardiothoracic Surgery, University of Louisville, Louisville, KY 40292, USA

3. Clinical Effectiveness Unit, The Royal College of Surgeons of England, London WC2A 3PE, UK

Abstract

Vein grafts are the most used conduits in coronary artery bypass grafting (CABG), even though many studies have suggested their lower patency compared to arterial alternatives. We have reviewed the techniques and technologies that have been investigated over the years with the aim of improving the quality of these conduits. We found that preoperative and postoperative optimal medical therapy and no-touch harvesting techniques have the strongest evidence for optimizing vein graft patency. On the other hand, the use of venous external support, endoscopic harvesting, vein preservation solution and anastomosis, and graft configuration need further investigation. We have also analyzed strategies to treat vein graft failure: when feasible, re-doing the CABG and native vessel primary coronary intervention (PCI) are the best options, followed by percutaneous procedures targeting the failed grafts.

Publisher

MDPI AG

Subject

General Medicine

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