Research Progress on Nanomaterials for Tissue Engineering in Oral Diseases

Author:

Jiang Tong12,Su Wen12,Li Yan3,Jiang Mingyuan12,Zhang Yonghong4,Xian Cory J.5ORCID,Zhai Yuankun12ORCID

Affiliation:

1. School of Stomatology, Henan University, Kaifeng 475000, China

2. Kaifeng Key Laboratory of Periodontal Tissue Engineering, Kaifeng 475000, China

3. Department of Pharmacy, Huaihe Hospital, Henan University, Kaifeng 475000, China

4. Department of Orthopaedics, The 2nd Hospital of Shanxi Medical University, Taiyuan 030001, China

5. UniSA Clinical and Health Sciences, University of South Australia, Adelaide, SA 5001, Australia

Abstract

Due to their superior antibacterial properties, biocompatibility and high conductivity, nanomaterials have shown a broad prospect in the biomedical field and have been widely used in the prevention and treatment of oral diseases. Also due to their small particle sizes and biodegradability, nanomaterials can provide solutions for tissue engineering, especially for oral tissue rehabilitation and regeneration. At present, research on nanomaterials in the field of dentistry focuses on the biological effects of various types of nanomaterials on different oral diseases and tissue engineering applications. In the current review, we have summarized the biological effects of nanoparticles on oral diseases, their potential action mechanisms and influencing factors. We have focused on the opportunities and challenges to various nanomaterial therapy strategies, with specific emphasis on overcoming the challenges through the development of biocompatible and smart nanomaterials. This review will provide references for potential clinical applications of novel nanomaterials in the field of oral medicine for the prevention, diagnosis and treatment of oral diseases.

Funder

Foundation of Science and Technology Department of Henan Province, China

Natural Science Foundation of Education Department of Henan Province, China

Foundation of the National Health Commission of Henan Province, China

Foundation of the Educational Administration Department of Henan University, China

Foundation of Science and Technology Department of Kaifeng City, Henan Province, China

Publisher

MDPI AG

Subject

Biomedical Engineering,Biomaterials

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