Management Strategies and Outcomes for Small Intestinal Neuroendocrine Tumours with Involvement of the Superior Mesenteric Vessels: A Systematic Review

Author:

Kmiotek Elizabeth1ORCID,Lakda Sakina2ORCID,Borakati Aditya3,Ogunbiyi Olagunju14,Mandair Dalvinder4,Caplin Martyn4,Toumpanakis Christos4,Mirnezami Reza14ORCID

Affiliation:

1. Department of Colorectal Surgery, The Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK

2. University College London Medical School, 74 Huntley Street, London WC1E 6DE, UK

3. Division of Surgery and Interventional Science, University College London, Royal Free Hospital Campus, 9th Floor, Pond Street, Hampstead, London NW3 2QG, UK

4. Neuroendocrine Tumour Unit, The Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK

Abstract

Small intestinal neuroendocrine tumours (SI-NETs) are the most common small intestinal tumours. A particularly challenging subset of these tumours is those that involve the superior mesenteric artery or vein for which the role and feasibility of surgery are often questioned. This systematic review aimed to identify and evaluate the management strategies used for these complex SI-NETs. The identified studies showed positive outcomes with surgery and multimodality therapy.

Publisher

MDPI AG

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