1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, 4710-057 Braga, Portugal
2. ICVS/3B’s—PT Government Associate Laboratory, 4806-909 Braga, Portugal
3. Department of Internal Medicine, São João Universitary Hospital Center, 4200-319 Porto, Portugal
4. Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal