Design, Synthesis, and Biological Assessment of Novel Vanillin-Isoxazole Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptor-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Assessment of Novel Vanillin-Isoxazole Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptor

Published:2023-11-15 Issue: Volume: Page:
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Container-title:ECSOC 2023
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Author:

Stabile Santiago¹^ORCID,Chrestia Juan Facundo²^ORCID,Radivoy Gabriel¹^ORCID,Bouzat Cecilia²

Affiliation:

1. Instituto de Química del Sur, INQUISUR (CONICET-UNS), NANOSYN, Departamento de Química, Universidad Nacional del Sur, Avda. Alem 1253, Bahía Blanca 8000, Argentina

2. Departamento de Biología, Bioquímica y Farmacia, Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB), Universidad Nacional del Sur-Consejo Nacional de Investigaciones Científicas y Técnicas (UNS-CONICET), Camino La Carrindanga Km 7, Bahía Blanca 8000, Argentina

Publisher

MDPI

Link

https://www.mdpi.com/2673-4583/14/1/65/pdf

Reference7 articles.

1. Flavonoids as Positive Allosteric Modulators of α7 Nicotinic Receptors;Nielsen;Neuropharmacology,2019

2. Ximenis, M., Mulet, J., Sala, S., Sala, F., Criado, M., González-Muñiz, R., and Pérez de Vega, M.J. (2021). Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as α7 nAChRs Positive Allosteric Modulators. Int. J. Mol. Sci., 22.

3. A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor: In Vitro and In Vivo Characterization;Hurst;J. Neurosci.,2005

4. One-Pot Copper(I)-Catalyzed Synthesis of 3,5-Disubstituted Isoxazoles;Hansen;J. Org. Chem.,2005

5. Design, Synthesis, and Functional Evaluation of a Novel Series of Phosphonate-Functionalized 1,2,3-Triazoles as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors;Nielsen;ACS Chem. Neurosci.,2020