Endoscopic Management of Strictures in Crohn’s Disease: An Unsolved Case

Author:

Coppola Gaetano12,Principessa Chiara2,Di Vincenzo Federica12ORCID,Puca Pierluigi12ORCID,Del Gaudio Angelo12,Capobianco Ivan12ORCID,Bartocci Bianca12,Papa Alfredo12ORCID,Cammarota Giovanni12,Lopetuso Loris Riccardo123ORCID,Scaldaferri Franco12ORCID

Affiliation:

1. CEMAD—IBD Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy

2. Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, 00168 Rome, Italy

3. Dipartimento di Medicina e Scienze dell’Invecchiamento, Università degli Studi “G. D’Annunzio”, 66100 Chieti, Italy

Abstract

Crohn’s disease (CD) is a chronic inflammatory disease associated with a significant burden in terms of quality of life and health care costs. It is frequently associated with several complications, including the development of intestinal strictures. Stricturing CD requires a careful multidisciplinary approach involving medical therapy and surgery, still posing a continuous management challenge; in this context, endoscopic treatment represents a valuable, in-between opportunity as a minimally invasive strategy endorsed by extensive yet heterogeneous evidence and evolving research and techniques. This review summarizes current knowledge on the role of therapeutic endoscopy in stricturing CD, focusing on evidence gaps, recent updates, and novel techniques intended for optimizing efficacy, safety, and tailoring of this approach in the view of precision endoscopy.

Publisher

MDPI AG

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