The Longevity Protein Klotho: A Promising Tool to Monitor Lifestyle Improvements-Reference-Cited by-同舟云学术

The Longevity Protein Klotho: A Promising Tool to Monitor Lifestyle Improvements

Published:2023-11-16 Issue:11 Volume:13 Page:1157
ISSN:2218-1989
Container-title:Metabolites
language:en
Short-container-title:Metabolites

Author:

Paquette Jean-Sébastien¹²³^ORCID,Rhéaume Caroline²³^ORCID,Cordeau Pierre³,Moulin Julie-Alexandra³,Audet-Walsh Etienne⁴^ORCID,Blanchette Virginie³⁵^ORCID,Drouin-Chartier Jean-Philippe⁶⁷^ORCID,Toi Alfred-Kodjo³,Tremblay Angelo⁶⁸⁹^ORCID

Affiliation:

1. Primary Care Research and Innovation Laboratory (Laboratoire ARIMED), Groupe de Médecine de Famille Universitaire du Nord de Lanaudière, Centre Intégré de Santé et de Services Sociaux de Lanaudière, Joliette, QC J6E 5X7, Canada

2. Department of Family Medicine and Emergency Medicine, Faculty of Medicine, Laval University, Québec City, QC G1V 0A6, Canada

3. Vitam, Research Center on Sustainable Health, Université Laval, Québec City, QC G1V 0A6, Canada

4. Département de Médecine Moléculaire, Faculté de Médecine, Université Laval, Québec City, QC G1V 0A6, Canada

5. Department of Human Kinetics and Podiatric Medicine, Université du Québec à Trois-Rivières, Trois-Rivières, QC G1V 0A6, Canada

6. NUTRISS (Nutrition, Health and Society) Research Centre, Institute on Nutrition and Functional Foods (INAF), Laval University, Québec City, QC G1V 0A6, Canada

7. Faculty of Pharmacy, Laval University, Québec City, QC G1V 0A6, Canada

8. Department of Kinesiology, Faculty of Medicine, Université Laval, Quebec City, QC G1V 0A6, Canada

9. Centre de Recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Quebec City, QC G1V 4G5, Canada

Abstract

Aging is not a disease; it is a natural evolution of human physiology. Medical advances have extended our life expectancy, but chronic diseases and geriatric syndrome continue to affect the increasingly aging population. Yet modern medicine perpetuates an approach based on treatment rather than prevention and education. In order to help solve this ever-growing problem, a new discipline has emerged: lifestyle medicine. Nutrition, physical activity, stress management, restorative sleep, social connection, and avoidance of risky substances are the pillars on which lifestyle medicine is founded. The aim of this discipline is to increase healthspan and reduce the duration of morbidity by making changes to our lifestyle. In this review, we propose the use of klotho protein as a novel biomarker for lifestyle medicine in order to quantify and monitor the health status of individuals, as no integrative tool currently exists.

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

https://www.mdpi.com/2218-1989/13/11/1157/pdf

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