HCV Genotype Has No Influence on the Incidence of Diabetes—EpiTer Multicentre Study

Author:

Rajewski PawełORCID,Zarębska-Michaluk DorotaORCID,Janczewska Ewa,Gietka Andrzej,Mazur Włodzimierz,Tudrujek-Zdunek Magdalena,Tomasiewicz Krzysztof,Belica-Wdowik Teresa,Baka-Ćwierz Barbara,Dybowska DorotaORCID,Halota Waldemar,Lorenc Beata,Sitko Marek,Garlicki Aleksander,Berak Hanna,Horban Andrzej,Orłowska Iwona,Simon Krzysztof,Socha Łukasz,Wawrzynowicz-Syczewska MartaORCID,Jaroszewicz Jerzy,Deroń Zbigniew,Czauż-Andrzejuk Agnieszka,Citko Jolanta,Krygier RafałORCID,Piekarska Anna,Laurans Łukasz,Dobracki Witold,Białkowska Jolanta,Tronina Olga,Wietlicka-Piszcz Magdalena,Pawłowska MałgorzataORCID,Flisiak RobertORCID

Abstract

HCV infection is one of the main reasons for liver cirrhosis and hepatocellular carcinoma. In recent years, one finds more and more extrahepatic manifestations of HCV infection, including its possible influence on the development of diabetes. In the presented work, one finds the frequency analysis of the incidence of diabetes among 2898 HCV infected patients treated in Poland, and the assessment of their relevance to the HCV genotype and the progression of fibrosis. The results indicate that the hepatitis C infection seems to be a risk factor for diabetes in persons with more advanced liver fibrosis, for older people, and for the male gender. Thus, one found no differences regarding the frequency of its incidence depending on HCV genotype, including genotype 3.

Publisher

MDPI AG

Subject

General Medicine

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