Hepatitis E Virus in Livestock—Update on Its Epidemiology and Risk of Infection to Humans

Author:

Turlewicz-Podbielska Hanna1ORCID,Augustyniak Agata1ORCID,Wojciechowski Jarosław2,Pomorska-Mól Małgorzata1ORCID

Affiliation:

1. Department of Preclinical Sciences and Infectious Diseases, Poznan University of Life Sciences, Wolynska 35, 60-637 Poznan, Poland

2. VETPOL SP. Z.O.O., Grabowa 3, 86-300 Grudziądz, Poland

Abstract

Hepatitis E virus (HEV) is a public health problem worldwide and an important food pathogen known for its zoonotic potential. Increasing numbers of infection cases with human HEV are caused by the zoonotic transmission of genotypes 3 and 4, mainly by consuming contaminated, undercooked or raw porcine meat. Pigs are the main reservoir of HEV. However, it should be noted that other animal species, such as cattle, sheep, goats, and rabbits, may also be a source of infection for humans. Due to the detection of HEV RNA in the milk and tissues of cattle, the consumption of infected uncooked milk and meat or offal from these species also poses a potential risk of zoonotic HEV infections. Poultry infected by avian HEV may also develop symptomatic disease, although avian HEV is not considered a zoonotic pathogen. HEV infection has a worldwide distribution with different prevalence rates depending on the affected animal species, sampling region, or breeding system.

Funder

Statutory funding of the Department of Preclinical Sciences and Infectious Diseases, Faculty of Veterinary Medicine and Animal Science, Poznan University of Life Sciences.

Publisher

MDPI AG

Subject

General Veterinary,Animal Science and Zoology

Reference215 articles.

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2. European Centre for Disease Prevention and Control (2023, September 15). Available online: https://www.ecdc.europa.eu/en/news-events/ecdc-report-10-fold-increase-hepatitis-e-cases-eueea-between-2005-and-2015.

3. Hepatitis E virus in blood components: A prevalence and transmission study in southeast England;Hewitt;Lancet,2014

4. Public Health England (2023, August 17). Department for Environment Food & Rural Affairs: Zoonoses Report UK, Available online: https://assets.publishing.service.gov.uk/media/5a7f205940f0b6230268d97e/pb13987-zoonoses-report-2013.pdf.

5. Comparative Seroprevalence of Hepatitis A and E Viruses in Blood Donors from Wielkopolska Region, West-Central Poland;Bura;Pol. J. Microbiol.,2018

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