Advances in Simple and Chiral-HPLC Methods for Antiallergic Drugs and Chiral Recognition Mechanism

Author:

Ali Imran1ORCID,Alam Syed Dilshad2ORCID,Raja Rupak3,Khan Shafat Ahmad3ORCID,Anjum Rushda3,Jain Arvind Kumar3,Aboul-Enein Hassan Y.4ORCID,Locatelli Marcello5ORCID

Affiliation:

1. Department of Chemistry, Jamia Millia Islamia, New Delhi 110025, India

2. Jubilant Biosys Limited, Knowledge Park-II, Greater Noida 201310, India

3. Division of Chemistry, School of Basic and Applied Sciences, Galgotias University, Greater Noida 201310, India

4. Pharmaceutical and Medicinal Chemistry Department, National Research Centre, Dokki, Cairo 12311, Egypt

5. Department of Pharmacy, Analytical and Bioanalytical Chemistry, University “G. d’Annunzio” of Chieti-Pescara, Build B, Level 2, Via dei Vestini, 31, 66100 Chieti, Italy

Abstract

Among many diseases, allergy appears to be a serious problem for human beings. Various forms of allergic disorders make people tense, leading to some other health issues. Many medications, including nonracemic and racemic ones, are used to treat this problem. It is important to have exact analysis strategies just to see any medication side effects, plasma profiles, and working efficiency. Therefore, efforts are made to review simple and chiral HPLC methods for antiallergic drugs; HPLC is the best analytical technique. The highlights in this article include the world scenario, causes of allergy, the effect of allergy on the economy, the mechanism of allergy in humans, classes of antiallergic drugs, simple drugs, chiral drugs, analysis by HPLC, and the chiral recognition mechanism. Moreover, attempts are also made to highlight the management of allergies and future perspectives.

Publisher

MDPI AG

Subject

General Medicine

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