Role of Silver Nitrate Spray for Skin Wound Care in Patients with Toxic Epidermal Necrolysis: Our Experience in 4 Patients-Reference-Cited by-同舟云学术

Role of Silver Nitrate Spray for Skin Wound Care in Patients with Toxic Epidermal Necrolysis: Our Experience in 4 Patients

Published:2023-12-14 Issue:12 Volume:13 Page:2341
ISSN:2075-1729
Container-title:Life
language:en
Short-container-title:Life

Author:

Martinez Jose Dario¹^ORCID,Cardenas Jesus Alberto²,Soria Manuel³,Saenz Luis Manuel⁴^ORCID,Estrada Kattya⁴,Delgado Sergio Maximo⁴,Ionescu Marius-Anton⁵^ORCID,Busila Camelia⁶⁷,Tatu Alin Laurentiu⁷⁸⁹^ORCID

Affiliation:

1. Department of Internal Medicine, Faculty of Medicine, University Hospital José Eleuterio González, University Autonomous of Nuevo León, Monterrey 66455, Mexico

2. Department of Rheumatology, Faculty of Medicine, University Hospital José Eleuterio González, University Autonomous of Nuevo León, Monterrey 66455, Mexico

3. Dermatology Department, Hospital Civil, Guadalajara 44630, Mexico

4. Medical Students, Faculty of Medicine, University Hospital José Eleuterio González, University Autonomous of Nuevo León, Monterrey 64460, Mexico

5. Department of Dermatology, University Hospital Saint Louis, 75010 Paris, France

6. “Sf. Ioan” Emergency Clinical Paediatric Hospital, 800179 Galati, Romania

7. Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, 800008 Galati, Romania

8. Dermatology Department, “SfantaCuvioasaParascheva” Hospital of Infectious Diseases, 800179 Galati, Romania

9. Multidisciplinary Integrated Center of Dermatological Interface Research MIC-DIR (Centrul Integrat Multidisciplinar de Cercetare de InterfataDermatologica—CIM-CID), “Dunărea de Jos” University, 800201 Galati, Romania

Abstract

Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of severe cutaneous adverse reactions to drugs (SCARs) with several international recommendations for global medical management, ranging from pharmacological systemic therapy to skin wound care. There is no defined best management of the skin wounds in SJS/TEN. The care of wounds is essential to initiate re-epithelialization. Our objective is to improve the cicatrization process, avoiding scarring due to deepening of the wounds, as well as prevent infections, achieve pain control, and avoid loss of serum proteins, fluids, and electrolytes. In this retrospective case series, we highlight the value of systemic therapy and the use of silver nitrate for wound management in four patients with TEN.

Funder

“Dunarea de Jos” University

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

Link

https://www.mdpi.com/2075-1729/13/12/2341/pdf

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