Special Issue: “Functionalized Nanomaterials and Structures for Biomedical Applications”
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Published:2023-12-05
Issue:24
Volume:16
Page:7521
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ISSN:1996-1944
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Container-title:Materials
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language:en
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Short-container-title:Materials
Author:
Balaure Paul Cătălin1ORCID
Affiliation:
1. “C.D. Nenițescu” Department of Organic Chemistry, Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 011061 Bucharest, Romania
Abstract
Nanoscale drug formulations are under wider and wider investigation due to their multiple unique advantages, such as stealth properties which avoid opsonization in the blood stream; specific ligand guided drug delivery to injured cells and tissues; on-demand release in sharp response to a series of endogenous and exogenous stimuli, allowing for predetermined programmed delivery to specific loci in the body and possible timing with circadian rhythms; increased cellular uptake due to their small dimensions and the possibility of intracellular delivery of the therapeutic cargo, especially when functionalized with cell penetrating agents; increased stability in biological fluids; augmented bioavailability; and tailored pharmacokinetics and pharmacodynamics [...]
Subject
General Materials Science
Reference11 articles.
1. Tejada, G., Calvo, N.L., Morri, M., Sortino, M., Lamas, C., Álvarez, V.A., and Leonardi, D. (2023). Miconazole Nitrate Microparticles in Lidocaine Loaded Films as a Treatment for Oropharyngeal Candidiasis. Materials, 16, Available online: https://www.mdpi.com/1996-1944/16/9/3586. 2. Mubaiwa, B., Lerata, M.S., Sibuyi, N.R.S., Meyer, M., Samaai, T., Bolton, J.J., Antunes, E.M., and Beukes, D.R. (2023). Green Synthesized sAuNPs as a Potential Delivery Platform for Cytotoxic Alkaloids. Materials, 16. 3. Mikelashvili, V., Kekutia, S., Markhulia, J., Saneblidze, L., Maisuradze, N., Kriechbaum, M., and Almásy, L. (2023). Synthesis and Characterization of Citric Acid-Modified Iron Oxide Nanoparticles Prepared with Electrohydraulic Discharge Treatment. Materials, 16. 4. Rajamohan, R., Raorane, C.J., Kim, S.-C., and Lee, Y.R. (2023). One Pot Synthesis of Copper Oxide Nanoparticles for Efficient Antibacterial Activity. Materials, 16. 5. Valentin, M., Coibion, D., Vertruyen, B., Malherbe, C., Cloots, R., and Boschini, F. (2023). Macroporous Mannitol Granules Produced by Spray Drying and Sacrificial Templating. Materials, 16.
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