Role of Phosphodiesterases in Biology and Pathology 2.0-Reference-Cited by-同舟云学术

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Role of Phosphodiesterases in Biology and Pathology 2.0

Published:2024-05-14 Issue:10 Volume:25 Page:5339
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Giorgi Mauro¹,Pellegrini Manuela²^ORCID,Massimi Mara³^ORCID

Affiliation:

1. Department of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome, Piazzale A. Moro 5, 00185 Rome, Italy

2. Institute of Biochemistry and Cell Biology, IBBC-CNR, Via E. Ramarini 32, 00015 Monterotondo (RM), Italy

3. Department of Life, Health and Environmental Sciences, University of L’Aquila, Via Vetoio, 67100 L’Aquila, Italy

Abstract

Phosphodiesterases (PDEs) are ubiquitous enzymes that hydrolyse cAMP and cGMP second messengers temporally, spatially, and integratedly according to their expression and compartmentalization inside the cell [...]

Publisher

MDPI AG

Link

https://www.mdpi.com/1422-0067/25/10/5339/pdf

Reference21 articles.

1. Phosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotides;Lomas;Physiology,2014

2. Advances in targeting cyclic nucleotide phosphodiesterases;Maurice;Nat. Rev. Drug Discov.,2014

3. Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules;Bondarev;Front. Pharmacol.,2022

4. Beyond Erectile Dysfunction: cGMP-Specific Phosphodiesterase 5 Inhibitors for Other Clinical Disorders;Samidurai;Annu. Rev. Pharmacol. Toxicol.,2023

5. Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts;West;J. Am. Heart Assoc.,2019

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