Prunella vulgaris L.: An Updated Overview of Botany, Chemical Composition, Extraction Methods, and Biological Activities

Author:

Zholdasbayev Mussa E.1ORCID,Atazhanova Gayane A.1,Musozoda Safol2,Poleszak Ewa3ORCID

Affiliation:

1. School of Pharmacy, NJSC “Karaganda Medical University”, Gogol Street, 40, Karaganda 100000, Kazakhstan

2. Department of Pharmaceutical Technology and Pharmacology, Building No. 3, Tajik National University, Rudaki Avenue Street, 17, Dushanbe 734035, Tajikistan

3. Department of Applied and Social Pharmacy, Medical University of Lublin, st. Al. Racławickie 1, 20-059 Lublin, Poland

Abstract

Prunella vulgaris L. (PV) is a well-known renewable drug resource full of different groups of biologically active substances with a wide range of pharmacological actions and applications in medicine. In this review, we present an updated comprehensive overview of the botany, extracting methods, chemical composition, and pharmacological activity of different parts of PV extracts. As a result of this review, it was found that chemical composition of PV depends on various factors ranging from the part of the plant to the method of extraction. We also highlight extraction methods that have not been previously used for obtaining PV extracts and may have high scientific interest. With this review, we hope to guide present and future professionals and provide possible previously unexplored areas to find new solutions associated with PV plant.

Funder

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan

Publisher

MDPI AG

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference85 articles.

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5. Rosmarinic acid in Prunella vulgaris ethanol extract inhibits lipopolysaccharide-induced prostaglandin E2 and nitric oxide in RAW 264.7 mouse macrophages;Huang;J. Agric. Food Chem.,2009

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