Responsive DNA Nanostructures for Bioanalysis and Therapy

Author:

Wang Yingfei1,Zhang Yue2ORCID,Ju Huangxian1,Liu Ying13ORCID

Affiliation:

1. State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China

2. School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China

3. Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210023, China

Abstract

DNA nanostructures have been widely explored as an encouraging tool for bioanalysis and cancer therapy due to its structural programmability and good biocompatibility. The incorporation of stimulus-responsive modules enables the accurate targeting and flexible control of structure and morphology, which is benefit to precise bioanalysis and therapy. This mini review briefly discusses the advancements in stimuli-responsive DNA nanostructures construction and their applications in biomolecules sensing and cancer treatment.

Funder

National Natural Science Foundation of China

State Key Laboratory of Analytical Chemistry for Life Science

Publisher

MDPI AG

Subject

Organic Chemistry,Inorganic Chemistry,Electrochemistry,Chemistry (miscellaneous)

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