Long-Term Survival of a Child with Atypical Teratoid-Rhabdoid Tumor and Acute Lymphoblastic Leukemia: A Case Report-Reference-Cited by-同舟云学术

Long-Term Survival of a Child with Atypical Teratoid-Rhabdoid Tumor and Acute Lymphoblastic Leukemia: A Case Report

Published:2024-04-03 Issue:2 Volume:5 Page:184-193
ISSN:2673-4095
Container-title:Surgeries
language:en
Short-container-title:Surgeries

Author:

Andreevna Kolcheva Maria¹²,Vyacheslavovna Kumirova Ella¹³⁴,Valeryevna Gorbatykh Svetlana¹,Gunai Nariman Makhmudova¹,Igorevich Livshits Matvey¹,Yegorovich Chmutin Gennadiy¹²,Nikolaevich Kislyakov Alexey¹,Nikolaevich Umerenkov Viktor¹,Encarnacion Ramirez Manuel de Jesus²^ORCID,Montemurro Nicola⁵^ORCID

Affiliation:

1. State Budgetary Healthcare Institution of the City of Moscow “Morozovskaya Children’s City Clinical Hospital of the Department of Health of the City of Moscow”, 119049 Moscow, Russia

2. Department of Neurosurgery, Peoples’ Friendship University of Russia (RUDN University), 117198 Moscow, Russia

3. Russian Research Center of Radiology of the Ministry of Health of the Russian Federation, 117856 Moscow, Russia

4. Federal State Budgetary Institution “Russian Scientific Center of X-ray Radiology of the Ministry of Health of the Russian Federation”, 119485 Moscow, Russia

5. Department of Neurosurgery, Azienda Ospedaliero Universitaria Pisana, 56100 Pisa, Italy

Abstract

Atypical teratoid-rhabdoid tumor (AT/RT) is a rare but one of the most aggressive embryonal tumors of the central nervous system (CNS), most often occurring in children under 3 years of age. AT/RT accounts for about 1–2% of all CNS neoplasms and has a very poor prognosis, high risk of secondary tumor development, recurrence and/or metastasis in patients in remission and limited therapeutic potential. The clinical manifestations are usually symptoms of increased intracranial pressure. The mainstay of tumor treatment is complex chemotherapy combined with radiation therapy. A clinical case of sequential occurrence of two cancers (AT/RT and leukemia) in a 3-year-old girl is presented.

Publisher

MDPI AG

Link

https://www.mdpi.com/2673-4095/5/2/18/pdf

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