The Effect of COVID-19 on Gut Microbiota: Exploring the Complex Interplay and Implications for Human Health

Author:

Akter Shamima1,Tasnim Sa’dia2,Barua Rashu3ORCID,Choubey Mayank3ORCID,Arbee Shahida4,Mohib Mohammad Mohabbulla5ORCID,Minhaz Naofel6,Choudhury Ajanta7,Sarker Pallab8,Mohiuddin Mohammad Sarif3ORCID

Affiliation:

1. Department of Internal Medicine, St. Francis—Emory Healthcare, 2122 Manchester Expressway, Columbus, GA 31904, USA

2. Department of Immunology, Bangladesh University of Health Sciences, Darus Salam Road, Dhaka 1216, Bangladesh

3. Department of Foundations of Medicine, NYU Long Island School of Medicine, 101 Mineola Blvd., Mineola, NY 11501, USA

4. Institute for Molecular Medicine, Aichi Medical University, 1-Yazako, Karimata, Aichi, Nagakute 480-1103, Japan

5. Julius Bernstein Institute of Physiology, Medical School, Martin Luther University of Halle-Wittenberg, Magdeburger Straße 6, 06112 Halle, Germany

6. Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University Hospital, Dhaka 1000, Bangladesh

7. Department of Internal Medicine, Jamaica Hospital Medical Center, 8900 Van Wyck Expy, Queens, NY 11418, USA

8. Department of Internal Medicine, Sher-e-Bangla Medical College Hospital, Band Rd., Barishal 8200, Bangladesh

Abstract

The COVID-19 pandemic caused by the SARS-CoV-2 virus has led to significant global health implications. Although the respiratory manifestations of COVID-19 are widely recognized, emerging evidence suggests that the disease may also significantly affect the gut microbiota, the intricate community of bacteria that lives within the gastrointestinal system. This extensive article intends to investigate the impact of COVID-19 on the gut microbiota, examining the underlying mechanisms, clinical implications, and potential therapeutic interventions. Understanding the complex interactions between COVID-19 and the gut microbiota will help us to gain valuable insights into the broader consequences of this viral infection on human health.

Publisher

MDPI AG

Subject

Gastroenterology,Oncology,Immunology and Microbiology (miscellaneous),Hepatology

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