Immune-Cell-Based Therapy for COVID-19: Current Status-Reference-Cited by-同舟云学术

Immune-Cell-Based Therapy for COVID-19: Current Status

Published:2023-10-25 Issue:11 Volume:15 Page:2148
ISSN:1999-4915
Container-title:Viruses
language:en
Short-container-title:Viruses

Author:

Wang Yiyuan¹²³,Liang Qinghe¹²³,Chen Fengsheng¹²³,Zheng Jiehuang¹²³,Chen Yan¹²³,Chen Ziye¹²³,Li Ruopeng¹²³,Li Xiaojuan¹²³

Affiliation:

1. Laboratory of Anti-Inflammatory and Immunomodulatory Pharmacology, Innovation Program of Drug Research on Inflammatory and Immune Diseases, Southern Medical University, Guangzhou 510515, China

2. NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China

3. Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. The interplay between innate and adaptive immune responses plays a crucial role in managing COVID-19. Cell therapy has recently emerged as a promising strategy to modulate the immune system, offering immense potential for the treatment of COVID-19 due to its customizability and regenerative capabilities. This review provides an overview of the various subsets of immune cell subsets implicated in the pathogenesis of COVID-19 and a comprehensive summary of the current status of immune cell therapy in COVID-19 treatment.

Funder

National Natural Science Foundation of China

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

Link

https://www.mdpi.com/1999-4915/15/11/2148/pdf

Reference86 articles.

1. SARS-CoV-2 variant biology: Immune escape, transmission and fitness;Carabelli;Nat. Rev. Microbiol.,2023

2. The evolution of SARS-CoV-2;Markov;Nat. Rev. Microbiol.,2023

3. Respiratory sequelae of COVID-19: Pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation;Singh;Lancet Respir. Med.,2023

4. Immunological imprinting: Understanding COVID-19;Koutsakos;Immunity,2023

5. Altmann, D.M., Whettlock, E.M., Liu, S., Arachchillage, D.J., and Boyton, R.J. (2023). The immunology of long COVID. Nat. Rev. Immunol., ahead of print.