Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease-Reference-Cited by-全球学者库

Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease

Published:2024-01-09 Issue:2 Volume:13 Page:363
ISSN:2077-0383
Container-title:Journal of Clinical Medicine
language:en
Short-container-title:JCM

Author:

Maidana Daniela¹,Arroyo-Álvarez Andrea¹^ORCID,Arenas-Loriente Andrea²,Barreres-Martín Guillermo¹,Muñoz-Alfonso Carles¹,Bompart Berroteran Daznia¹^ORCID,Esteve Claramunt Francisca¹^ORCID,Blanco del Burgo Regina¹,Cepas-Guillén Pedro²^ORCID,Garcia-Blas Sergio¹³^ORCID,Bonanad Clara¹³^ORCID

Affiliation:

1. INCLIVA—Instituto de Investigación Sanitaria, Biomedical Research Institute, 46010 Valencia, Spain

2. Cardiology Department, Hospital Clinic Barcelona, 08036 Barcelona, Spain

3. Cardiology Department, Clinic University Hospital of Valencia, 46026 Valencia, Spain

Abstract

Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation is intricately linked with the aging process and plays a pivotal role in the evolution of atherosclerosis. Emerging anti-inflammatory therapies have shown promise in reducing ischemic events among high-risk populations. This review aims to explore the potential of targeted anti-inflammatory interventions in improving clinical outcomes and the quality of life for older patients with IHD.

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2077-0383/13/2/363/pdf

Reference94 articles.

1. Global Burden of 369 Diseases and Injuries in 204 Countries and Territories, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019;Murray;Lancet,2020

2. The Global Burden of Cardiovascular Diseases and Risk: A Compass for Future Health;Vaduganathan;J. Am. Coll. Cardiol.,2022

3. Epidemiology of Acute Coronary Syndromes in Spain: Estimation of the Number of Cases and Trends from 2005 to 2049;Elosua;Rev. Española De Cardiol. (Engl. Ed.),2013

4. Inflammation, Atherosclerosis, and Coronary Artery Disease;Hansson;N. Engl. J. Med.,2005

5. Frailty and Other Geriatric Conditions for Risk Stratification of Older Patients with Acute Coronary Syndrome;Sanchis;Am. Heart J.,2014