Prevalence of Hyperuricemia and Associated Cardiovascular Risk Factors in Elite Athletes Practicing Different Sporting Disciplines: A Cross-Sectional Study
-
Published:2024-01-18
Issue:2
Volume:13
Page:560
-
ISSN:2077-0383
-
Container-title:Journal of Clinical Medicine
-
language:en
-
Short-container-title:JCM
Author:
Di Gioia Giuseppe123ORCID, Crispino Simone Pasquale2ORCID, Maestrini Viviana14, Monosilio Sara14ORCID, Squeo Maria Rosaria1, Lemme Erika1, Segreti Andrea23ORCID, Serdoz Andrea1, Fiore Roberto1, Zampaglione Domenico1, Pelliccia Antonio1
Affiliation:
1. Institute of Sports Medicine and Science, National Italian Olympic Committee, Largo Piero Gabrielli 1, 00197 Rome, Italy 2. Department of Cardiovascular Sciences, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, 00128 Rome, Italy 3. Department of Movement, Human and Health Sciences, University of Rome “Foro Italico”, Piazza Lauro De Bosis 15, 00135 Rome, Italy 4. Department of Clinical, Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Abstract
Uricemia has been identified as an independent risk factor for cardiovascular disease. In the general population, hyperuricemia is associated with hypertension, endothelial dysfunction, and other cardiovascular risk (CVR) factors. Our aim was to explore the prevalence of hyperuricemia among Olympic athletes, evaluating the influence of sporting discipline and its correlation with CVR factors. We enrolled 1173 Olympic athletes classified into four disciplines: power, skill, endurance, and mixed. Clinical, anthropometric data, and complete blood test results were collected. Hyperuricemia was present in 4.4% of athletes, 0.3% were hypertensive, 11.7% had high-normal blood pressure values, 0.2% were diabetic, 1.2%. glucose intolerance, 8.2% active smokers, and 3% were obese. Males had a higher prevalence of hyperuricemia (5.3%) than females (3.4%) with no significant differences between different sporting disciplines (male, p = 0.412; female p = 0.561). Males with fat mass >22% presented higher uricemia (5.8 ± 1 vs. 5.3 ± 1 mg/dL, p = 0.010) like hypertensive athletes (6.5 ± 0.3 vs. 5.3 ± 1 mg/dL, p = 0.031), those with high-normal blood pressure (5.13 ± 1 vs. 4.76 ± 1.1 mg/dL, p = 0.0004) and those with glucose intolerance (6 ± 0.8 vs. 5.3 ± 1 mg/dL, p = 0.066). The study provides a comprehensive evaluation of hyperuricemia among Olympic athletes, revealing a modest prevalence, lower than in the general population. However, aggregation of multiple CVR factors could synergistically elevate the risk profile, even in a population assumed to be at low risk. Therefore, uric acid levels should be monitored as part of the CVR assessment in athletes.
Reference21 articles.
1. Uric acid and cardiovascular risk;Feig;N. Engl. J. Med.,2008 2. Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007-2008;Zhu;Arthritis Rheum.,2011 3. Prevalence of hyperuricemia and the population attributable fraction of modifiable risk factors: Evidence from a general population cohort in China;He;Front. Public Health,2022 4. Antelo-Pais, P., Prieto-Diaz, M.A., Mico-Perez, R.M., Pallares-Carratala, V., Velilla-Zancada, S., Polo-Garcia, J., Barquilla-Garcia, A., Ginel-Mendoza, L., Segura-Fragoso, A., and Vitelli-Storelli, F. (2022). Prevalence of Hyperuricemia and Its Association with Cardiovascular Risk Factors and Subclinical Target Organ Damage. J. Clin. Med., 12. 5. The relationship between anthropometric factors and hyperuricemia in adolescent athletes;Kuo;Obes. Res. Clin. Pract.,2021
|
|