Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases

Author:

Thakur Abhimanyu1,Shah Disheet2,Rai Deepika3ORCID,Parra Diana Carolina4ORCID,Pathikonda Spoorthy5,Kurilova Svetlana6,Cili Alma7

Affiliation:

1. Ben May Department for Cancer Research, Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA

2. Department of Pharmacology, Northwestern University, Chicago, IL 60208, USA

3. Smidt Heart Institute, Cedars-Sinai Medical Centre, Los Angeles, CA 90048, USA

4. Tropical Disease Laboratory, Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), São Paulo 13083-970, Brazil

5. Department of Chemistry, City University of Hong Kong, Hong Kong SAR, China

6. Office of Technology Management, University of Illinois Chicago, Chicago, IL 60612, USA

7. Clinic of Hematology, University of Medicine, University Hospital Center “Mother Teresa”, “Rr. e DIbres” Nr. 372, 1001 Tirane, Albania

Abstract

Exosomes are small extracellular nanovesicles that are released by cells, and their potential has been explored for use in cosmetics, skin care, tissue regeneration, and dermatological diseases. The therapeutic value of exosomes lies in their ability to modulate the microenvironment of cells, regulate gene expression, and induce cell differentiation, which can have a positive impact on skin health. In terms of cosmetics, exosomes have been used to reduce wrinkles, improve skin texture and hydration, and enhance skin elasticity, as well as to reduce inflammation and damage caused by UV radiation. Furthermore, exosomes have been used to promote tissue regeneration in skin wounds and to treat dermatological diseases such as systemic lupus erythematosus, psoriasis, atopic dermatitis, systemic sclerosis, pigment regulation, vitiligo, and hair growth. In this review, the therapeutic value of exosomes in the field of cosmetics, skin care, tissue regeneration, and dermatological diseases, has been elaborated. The existing literature demonstrated that with further research, exosomes may become a viable therapeutic option for many skin conditions.

Publisher

MDPI AG

Subject

Dermatology,Pharmaceutical Science,Aging,Chemical Engineering (miscellaneous),Surgery

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