Which Comes First, Nonalcoholic Fatty Liver Disease or Arterial Hypertension?

Author:

Golubeva Julia A.1,Sheptulina Anna F.12,Elkina Anastasia Yu.13ORCID,Liusina Ekaterina O.1,Kiselev Anton R.4ORCID,Drapkina Oxana M.12ORCID

Affiliation:

1. Department of Fundamental and Applied Aspects of Obesity, National Medical Research Center for Therapy and Preventive Medicine, 101990 Moscow, Russia

2. Department of Therapy and Preventive Medicine, A.I. Evdokimov Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia

3. Department of Intermediate Level Therapy, Saratov State Medical University, 410012 Saratov, Russia

4. Coordinating Center for Fundamental Research, National Medical Research Center for Therapy and Preventive Medicine, 101990 Moscow, Russia

Abstract

Non-alcoholic fatty liver disease (NAFLD) and arterial hypertension (AH) are widespread noncommunicable diseases in the global population. Since hypertension and NAFLD are diseases associated with metabolic syndrome, they are often comorbid. In fact, many contemporary published studies confirm the association of these diseases with each other, regardless of whether other metabolic factors, such as obesity, dyslipidemia, and type 2 diabetes mellites, are present. This narrative review considers the features of the association between NAFLD and AH, as well as possible pathophysiological mechanisms.

Funder

Russian Science Foundation

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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