Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy

Author:

Lupu Vasile Valeriu1ORCID,Jechel Elena1,Fotea Silvia2,Morariu Ionela Daniela3ORCID,Starcea Iuliana Magdalena1ORCID,Azoicai Alice1,Mocanu Adriana1,Mitrofan Elena Cristina4,Lupu Ancuta1ORCID,Munteanu Dragos5ORCID,Badescu Minerva Codruta5ORCID,Cuciureanu Magdalena6ORCID,Ioniuc Ileana1

Affiliation:

1. Department of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

2. Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University of Galati, 800008 Galati, Romania

3. Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

4. CF Clinical Hospital, 700506 Iasi, Romania

5. Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

6. Department of Pharmacology, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

Abstract

Asthma and adolescence are two sensitive points and are difficult to manage when they coexist. The first is a chronic respiratory condition, with frequent onset in early childhood (between 3 and 5 years), which can improve or worsen with age. Adolescence is the period between childhood and adulthood (12–19 years), marked by various internal and external conflicts and a limited capacity to understand and accept any aspect that is delimited by the pattern of the social circle (of the entourage) frequented by the individual. Therefore, the clinician is faced with multiple attempts regarding the management of asthma encountered during the adolescent period, starting from the individualization of the therapy to the control of compliance (which depends equally on the adverse reactions, quality of life offered and support of the close circle) and the social integration of the subject, communication probably having a more important role in the monitoring and evolution of the condition than the preference for a certain therapeutic scheme. Current statistics draw attention to the increase in morbidity and mortality among children with bronchial asthma, an aspect demonstrated by the numerous hospitalizations recorded, due either to an escalation in the severity of this pathology or to faulty management. The purpose of this article is to review the delicate aspects in terms of controlling symptoms and maintaining a high quality of life among teenagers.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

Reference125 articles.

1. Pediatric Asthma: A Global Epidemic;Serebrisky;Ann. Glob. Health,2019

2. National Center for Environmental Health (2023, June 30). Most Recent National Asthma Data, Available online: https://www.cdc.gov/asthma/most_recent_national_asthma_data.htm.

3. Prevalence of asthma among male 16 to 18-year-old adolescents in the Northern Borders Region of Saudi Arabia;Alruwaili;Electron. Physician,2018

4. Prevalence of Asthma symptoms and risk factors in adolescents. Journal of Human Growth and Development;Santana;J. Hum. Growth Dev.,2019

5. Asthma;Holgate;Nat. Rev. Dis. Primers,2015

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