Clinicopathological Outlines of Post-COVID-19 Pulmonary Fibrosis Compared with Idiopathic Pulmonary Fibrosis

Author:

Cîrjaliu Roxana-Elena12ORCID,Deacu Mariana23,Gherghișan Ioana14,Marghescu Angela-Ștefania56ORCID,Enciu Manuela23,Băltățescu Gabriela Izabela7ORCID,Nicolau Antonela Anca7ORCID,Tofolean Doina-Ecaterina12ORCID,Arghir Oana Cristina14ORCID,Fildan Ariadna-Petronela14

Affiliation:

1. Department of Pneumology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania

2. Clinical Emergency “St. Andrew” Hospital of Constanta, 900591 Constanta, Romania

3. Department of Anatomopathology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania

4. Pneumology Hospital of Constanta, 900002 Constanta, Romania

5. Department of Anatomopathology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania

6. Pneumology Institute “Marius Nasta”, 50158 Bucharest, Romania

7. Center for Research and Development of the Morphological and Genetic Studies of Malignant Pathology-CEDMOG, “Ovidius” University of Constanta, 900591 Constanta, Romania

Abstract

This review brings together the current knowledge regarding the risk factors and the clinical, radiologic, and histological features of both post-COVID-19 pulmonary fibrosis (PCPF) and idiopathic pulmonary fibrosis (IPF), describing the similarities and the disparities between these two diseases, using numerous databases to identify relevant articles published in English through October 2022. This review would help clinicians, pathologists, and researchers make an accurate diagnosis, which can help identify the group of patients selected for anti-fibrotic therapies and future therapeutic perspectives.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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