Blood Markers of Biological Age Evaluates Clinic Complex Medical Spa Programs

Author:

Isaev Fedor I.1ORCID,Sadykov Arsenii R.2,Moskalev Alexey34ORCID

Affiliation:

1. Kivach Clinic, 186202 Konchezero, Russia

2. Laboratory of Metabolomic Diagnostics of Meta-Metrix, 117630 Moscow, Russia

3. Institute of Biogerontology, Lobachevsky State University of Nizhny Novgorod, 603146 Nizhny Novgorod, Russia

4. Russian Research Clinical Center of Gerontology of the Russian National Research Medical University Named after N.I. Pirogov, 129226 Moscow, Russia

Abstract

Background: Kivach Clinic has developed a special medical spa program to prevent aging-related conditions in metabolic, cardio-vascular, and neurological states. Spa programs modify diet, physical activity, and lymphatic drainage, as it deteriorates with aging. We investigated its influence on the blood markers of biological age of patients during their stay to objectify the potential of spa treatment for influencing the risk of age-related events. Methods: The artificial deep learning model Aging.ai 3.0 was based on blood parameters. The change in the biological age of 43 patients was assessed after their 14-day spa treatment at Kivach Clinic. Results: Biological age decreased in 29 patients (median decrease: 8 years, mean: 8.83 years), increased in 10 patients (median increase: 3 years, mean: 5.33 years) and remained unchanged in 4 patients. Overall mean values for the entire patient group were as follows: median value was −3 years, and mean was −4.79 ± 1.2 years (p-value = 0.00025, t-test). Conclusions: The capability of specially selected medical spa treatment to reduce human biological age (assessed by Aging.AI 3.0) has been established.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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