The Association between Coagulation and Atrial Fibrillation

Author:

Rafaqat Saira1ORCID,Gluscevic Sanja2,Patoulias Dimitrios3ORCID,Sharif Saima1ORCID,Klisic Aleksandra45ORCID

Affiliation:

1. Department of Zoology (Molecular Physiology), Lahore College for Women University, Lahore 54600, Punjab, Pakistan

2. Department of Neurology, Clinical Center of Montenegro, 81000 Podgorica, Montenegro

3. Outpatient Department of Cardiometabolic Medicine, Second Department of Cardiology, Aristotle University of Thessaloniki, General Hospital “Hippokration”, 54642 Thessaloniki, Greece

4. Faculty of Medicine, University of Montenegro, 81000 Podgorica, Montenegro

5. Center for Laboratory Diagnostics, Primary Health Care Center, 81000 Podgorica, Montenegro

Abstract

The existing literature highlights the presence of numerous coagulation factors and markers. Elevated levels of coagulation factors are associated with both existing and newly diagnosed cases of atrial fibrillation (AF). However, this article summarizes the role of coagulation in the pathogenesis of AF, which includes fibrinogen and fibrin, prothrombin, thrombomodulin, soluble urokinase plasminogen activator receptor, von Willebrand factor, P-selectin, D-dimer, plasminogen activator inhibitor-1, and platelet activation. Coagulation irregularities play a significant role in the pathogenesis of AF.

Funder

Ministry of Education, Science and Innovations, Montenegro

Publisher

MDPI AG

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