COVID-19-Related Myocarditis: Are We There Yet? A Case Report of COVID-19-Related Fulminant Myocarditis

Author:

Pierri Alessandro12ORCID,Gagno Giulia12,Fluca Alessandra12,Radaelli Davide2ORCID,Bonuccelli Diana3,Giusti Laura4,Bulfoni Michela5,Beltrami Antonio P.5ORCID,Aleksova Aneta12ORCID,D’Errico Stefano2

Affiliation:

1. Cardiothoracovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, 34139 Trieste, Italy

2. Department of Medical, Surgical and Health Sciences, University of Trieste, 34139 Trieste, Italy

3. Department of Legal Medicine, Azienda USL Toscana Nordovest, 55100 Lucca, Italy

4. Department of Human Pathology, San Luca Hospital, Azienda USL Toscana Nordovest, 55100 Lucca, Italy

5. Institute of Clinical Pathology, Academic Hospital “Santa Maria della Misericordia”, ASUFC, Department of Medicine (DAME), University of Udine, 33100 Udine, Italy

Abstract

There is increasing evidence of cardiac involvement in COVID-19 cases, with a broad range of clinical manifestations spanning from acute life-threatening conditions such as ventricular dysrhythmias, myocarditis, acute myocardial ischemia and pulmonary thromboembolism to long-term cardiovascular sequelae. In particular, acute myocarditis represents an uncommon but frightening complication of SARS-CoV-2 infection. Even if many reports of SARS CoV-2 myocarditis are present in the literature, the majority of them lacks histological confirmation of cardiac injury. Here, we report a case of a young lady, who died suddenly a few days after testing positive for SARS-CoV-2, whose microscopic and genetics features suggested a direct cardiac involvement compatible with fulminant myocarditis.

Funder

Regione Friuli Venezia Giulia

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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