Recent Advances in Diagnostic Approaches for Mucormycosis

Author:

Safiia Jawad1ORCID,Díaz Marco Aurelio123ORCID,Alshaker Hassan13ORCID,Atallah Christine J.13,Sakr Paul13,Moshovitis Dimitrios G.12ORCID,Nawlo Ahmad13ORCID,Franceschi Andres E.123ORCID,Liakos Alexis12,Koo Sophia123

Affiliation:

1. Brigham and Women’s Hospital, Boston, MA 02115, USA

2. Dana-Farber Cancer Institute, Boston, MA 02215, USA

3. Harvard Medical School, Boston, MA 02115, USA

Abstract

Mucormycosis, an invasive fungal infection caused by members of the order Mucorales, often progresses fulminantly if not recognized in a timely manner. This comprehensive review discusses the latest developments in diagnostic approaches for mucormycosis, from traditional histopathology and culture-based methods to advanced and emerging techniques such as molecular assays, imaging, serology, and metabolomics. We discuss challenges in the diagnosis of mucormycosis and emphasize the importance of rapid and accurate identification of this life-threatening infection.

Publisher

MDPI AG

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