Quantitative Characterization of Age-Related Changes in Peripheral Vessels of a Human Palm Using Raster-Scan Optoacoustic Angiography

Author:

Perekatova Valeriya,Kirillin MikhailORCID,Nemirova Svetlana,Orlova Anna,Kurnikov AlexeyORCID,Khilov AleksandrORCID,Pavlova Ksenia,Kazakov Viacheslav,Vildanov VadimORCID,Turchin IlyaORCID,Subochev Pavel

Abstract

The analysis of age-related changes in skin vessels based on optoacoustic angiographic images during the in vivo skin monitoring of healthy volunteers at different ages is reported. As a result of a quantitative analysis of the three-dimensional OA images, the age-associated differences in the following image parameters were revealed: image intensity, ratio of blood content at different characteristics depths, total vessel length, and number of branches. The reported approach can be effectively employed for automatic assessment and monitoring of age-related vascular changes in the skin and underlying tissues.

Funder

Centre of Excellence “Center of Photonics” funded by the Ministry of Science and High Education of the Russian Federation

Publisher

MDPI AG

Subject

Radiology, Nuclear Medicine and imaging,Instrumentation,Atomic and Molecular Physics, and Optics

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