Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study

Author:

Garbuzova Evgeniia V.1ORCID,Shcherbakova Lilia V.1,Rymar Oksana D.1ORCID,Khudiakova Alyona D.1ORCID,Shramko Victoria S.1ORCID,Ragino Yulia I.1ORCID

Affiliation:

1. Research Institute of Internal and Preventive Medicine—Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM—Branch of IC&G SB RAS), 630089 Novosibirsk, Russia

Abstract

Background: It is important to determine the influence of traditional risk factors on the development of type 2 diabetes mellitus (T2DM) in young adults. Goal of the research: To study the incidence of T2DM and factors that increase the risk of its occurrence during the observation of a cohort of young adults. Materials and methods: 1341 people aged 25–44 were included in the study from 2013 to 2017, of whom 622 were men (46.4%). The examination included anamnesis, anthropometric data, and a blood test. Cases of developed T2DM were identified by comparing the Diabetes Mellitus Register, medical records of patients, and the database of examined individuals from 2019 to 2023. T2DM Results: In the examined population, 11 participants (0.82%) developed T2DM. The prevalence of T2DM was 0.96% in men and 0.69% in women. Patients with T2DM had a higher waist circumference, BMI, SBP, TG, and lower HDL than patients without T2DM, and were also less likely to have a higher education. The risk of developing T2DM increases 6.5 times at a BMI of ≥30 kg/m2, and 5.2 times at a TG level of ≥1.7 mmol/L, regardless of other risk factors. In the absence of a higher education, the risk of developing T2DM is increased by 5.6 times. Conclusion: In young people, high triglyceride levels, obesity, and a low level of education are associated with the risk of developing type 2 diabetes, regardless of other factors.

Funder

Russian Science Foundation

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

Reference34 articles.

1. Global Burden of Disease Study 2013 Collaborators, Vos, T., Allen, C., Arora, M., Barber, R.M., Bhutta, Z.A., Brown, A., Liang, X., Kawashima, T., and Coggeshall, M. (2015). Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet, 386, 743–800.

2. Federal targeted programme ‘Prevention and Management of Socially Significant Diseases (2007–2012)’: Results of the ‘Diabetes mellitus’ sub-programme;Dedov;Diabetes Mellit.,2013

3. The prevalence of type 2 diabetes mellitus in the adult population of Russia (NA-TION study);Dedov;Diabetes Mellit.,2016

4. International Diabetes Federation (IDF) (2017). IDF Diabetes Atlas, International Diabetes Fedration. [8th ed.].

5. Epidemiological characteristics of diabetes mellitus in the Russian Federation: Clinical and statistical analysis according to the Federal diabetes register data of 01.01.2021;Dedov;Diabetes Mellit.,2021

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