The Influence of SARS-CoV-2 Infection on Acute Myocardial Infarction Outcomes-Reference-Cited by-同舟云学术

The Influence of SARS-CoV-2 Infection on Acute Myocardial Infarction Outcomes

Published:2023-09-11 Issue:18 Volume:12 Page:5899
ISSN:2077-0383
Container-title:Journal of Clinical Medicine
language:en
Short-container-title:JCM

Author:

Hrycek Eugeniusz¹²,Walawska-Hrycek Anna³^ORCID,Hamankiewicz Maciej⁴,Milewski Krzysztof⁵,Nowakowski Przemysław¹⁶^ORCID,Buszman Piotr²⁵,Żurakowski Aleksander¹²

Affiliation:

1. American Heart of Poland, Topolowa 16, 32-500 Chrzanów, Poland

2. Department of Cardiology, Faculty of Medical Sciences, Andrzej Frycz Modrzewski Kraków University, 30-705 Kraków, Poland

3. Department of Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland

4. American Heart of Poland, Warszawska 52, 40-008 Katowice, Poland

5. American Heart of Poland, Armii Krajowej 101, 43-316 Bielsko-Biała, Poland

6. Department of Vascular Surgery, Faculty of Medical Sciences, University of Technology, Rolna 43, 40-555 Katowice, Poland

Abstract

Background: This multicenter retrospective study with a control group was designed to assess the influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the outcomes of patients with myocardial infarction (MI). Methods: A total of 129 patients with COVID-19 who were treated for MI were included in this study. The control group comprised 129 comparable patients without SARS-CoV-2 infection. The in-hospital, out-of-hospital, and overall mortality were analyzed. Results: A total of thirty-one (24%) patients died in the study group, and two (1.6%) patients died in the control group (OR = 20.09; CI: 4.69–85.97; p < 0.001). Similar results were observed in all analyzed patient subgroups. Multivariable Cox regression analysis confirmed the significant influence of SARS-CoV-2 infection on in-hospital outcomes (HR: 8.48459; CI: 1.982–36.320; p = 0.004). Subanalysis of the groups with COVID-19 plus ST-elevation MI (STEMI) or non-ST-elevation MI (NSTEMI) revealed comparable mortality rates: 14 (21.12%) patients in the NSTEMI group and 17 (26.98%) patients in the STEMI subgroup died (OR: 1.3; CI: 0.56–3.37; p = 0.45). During out-of-hospital observation, no differences in mortality were observed (OR: 0.77; CI: 0.11–4.07; p = 0.73). Conclusions: SARS-CoV-2 infection affects the in-hospital outcomes of patients with both MI and COVID-19, regardless of MI type (STEMI vs. NSTEMI).

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2077-0383/12/18/5899/pdf

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