Application of Nanomaterials in the Production of Biomolecules in Microalgae: A Review

Author:

Yuan Xiaolong1,Gao Xiang1ORCID,Liu Chang1,Liang Wensheng1,Xue Huidan1,Li Zhengke1,Jin Haojie2ORCID

Affiliation:

1. School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi’an 710021, China

2. The College of Forestry, Beijing Forestry University, Beijing 100083, China

Abstract

Nanomaterials (NMs) are becoming more commonly used in microalgal biotechnology to empower the production of algal biomass and valuable metabolites, such as lipids, proteins, and exopolysaccharides. It provides an effective and promising supplement to the existing algal biotechnology. In this review, the potential for NMs to enhance microalgal growth by improving photosynthetic utilization efficiency and removing reactive oxygen species is first summarized. Then, their positive roles in accumulation, bioactivity modification, and extraction of valuable microalgal metabolites are presented. After the application of NMs in microalgae cultivation, the extracted metabolites, particularly exopolysaccharides, contain trace amounts of NM residues, and thus, the impact of these residues on the functional properties of the metabolites is also evaluated. Finally, the methods for removing NM residues from the extracted metabolites are summarized. This review provides insights into the application of nanotechnology for sustainable production of valuable metabolites in microalgae and will contribute useful information for ongoing and future practice.

Funder

Shaanxi Province Qin Chuangyuan “Scientist + Engineer” Team Construction Project

Key Research and Development Program of Shaanxi Province

Publisher

MDPI AG

Subject

Drug Discovery,Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science

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