Outcomes of Thoracoscopic Lobectomy after Recent COVID-19 Infection

Author:

Leonardi Beatrice1ORCID,Sagnelli Caterina2ORCID,Natale Giovanni1,Leone Francesco1,Noro Antonio1,Opromolla Giorgia1,Capaccio Damiano3,Ferrigno Francesco4,Vicidomini Giovanni1,Messina Gaetana1,Di Crescenzo Rosa Maria5,Sica Antonello6ORCID,Fiorelli Alfonso1ORCID

Affiliation:

1. Thoracic Surgery Unit, University of Campania Luigi Vanvitelli, 80131 Naples, Italy

2. Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, 80131 Naples, Italy

3. Pneumology Unit, Eboli Hospital; Eboli, 84025 Salerno, Italy

4. COVID-19 Hospital “M. Scarlato”, Department of Pneumology, 84018 Scafati, Italy

5. Anatomo-Pathology Unit, University Federico II, 80131 Naples, Italy

6. Department of Precision Medicine, University of Campania Luigi Vanvitelli, 80131 Naples, Italy

Abstract

Background: The COVID-19 outbreak had a massive impact on lung cancer patients with the rise in the incidence and mortality of lung cancer. Methods: We evaluated whether a recent COVID-19 infection affected the outcome of patients undergoing thoracoscopic lobectomy for lung cancer using a retrospective observational mono-centric study conducted between January 2020 and August 2022. Postoperative complications and 90-day mortality were reported. We compared lung cancer patients with a recent history of COVID-19 infection prior to thoracoscopic lobectomy to those without recent COVID-19 infection. Univariable and multivariable analyses were performed. Results: One hundred and fifty-three consecutive lung cancer patients were enrolled. Of these 30 (19%), had a history of recent COVID-19 infection prior to surgery. COVID-19 was not associated with a higher complication rate or 90-day mortality. Patients with recent COVID-19 infection had more frequent pleural adhesions (p = 0.006). There were no differences between groups regarding postoperative complications, conversion, drain removal time, total drainage output, and length of hospital stay. Conclusions: COVID-19 infection did not affect the outcomes of thoracoscopic lobectomy for lung cancer. The treatment of these patients should not be delayed in case of recent COVID-19 infection and should not differ from that of the general population.

Publisher

MDPI AG

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,Molecular Biology,Immunology and Allergy

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