Bovine Papillomavirus Type 1 Infection in an Equine Congenital Papilloma

Author:

Maggi Raffaella1,De Paolis Livia2ORCID,De Santis Daria3,Vellone Valerio Gaetano4ORCID,De Ciucis Chiara Grazia2,Fruscione Floriana2ORCID,Mazzocco Katia4ORCID,Ghelardi Alessandro5ORCID,Marruchella Giuseppe6ORCID,Razzuoli Elisabetta2ORCID

Affiliation:

1. Veterinary Practitioner, Via Cassia 829, 00189 Rome, Italy

2. Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, National Reference Center of Veterinary and Comparative Oncology (CEROVEC), Piazza Borgo Pila 29/34, 16129 Genova, Italy

3. Veterinary Practitioner, Via San Manno 19, 03024 Cepranno, Italy

4. U.O.C. Anatomia Patologica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy

5. Azienda Usl Toscana-Ovest, UOC Ostetricia e Ginecologia, Ospedale Apuane, 54100 Massa, Italy

6. Faculty of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy

Abstract

Papillomas are benign epithelial lesions protruding on the epithelial surfaces as finger-like or warty projections. These lesions are often caused by papillomavirus (PV) infection. Congenital papillomas have been reported in foals. However, to date, no evidence of PV infection has been provided. In the present paper, we describe the main clinical–pathological features of a congenital papilloma observed in a foal. In addition, biomolecular tests demonstrated BPV1 infection in the case under study. Such data stimulate further investigations, even on archived samples, aiming to clarifying the etiology of equine congenital papilloma and the clinical relevance, if any, of BPV1 vertical transmission in horses.

Funder

Italian Ministry of Health and the Liguria Region

APC

Publisher

MDPI AG

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,Molecular Biology,Immunology and Allergy

Reference37 articles.

1. Kumar, V., Abbas, A.K., and Fausto, N. (2005). Pathologic Basis of Disease, Elsevier Saunders. [7th ed.].

2. Classification of papillomaviruses;Fauquet;Virology,2004

3. Maxie, M.G. (2015). Pathology of Domestic Animals, Elsevier. [6th ed.].

4. Scott, D.W. (1998). Large Animal Dermatology, W.B. Saunders Company.

5. Equine sarcoids;Goodrich;Vet. Clin. N. Am. Equine Pract.,1998

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