Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma-Reference-Cited by-同舟云学术

Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma

Published:2023-05-10 Issue:10 Volume:11 Page:1373
ISSN:2227-9032
Container-title:Healthcare
language:en
Short-container-title:Healthcare

Author:

Perelli Federica¹,Vizzielli Giuseppe²³^ORCID,Cavaliere Anna Franca⁴,Restaino Stefano²^ORCID,Scambia Giovanni⁵,Zannoni Gian Franco⁶⁷^ORCID,Arciuolo Damiano⁶,Gallotta Valerio⁵

Affiliation:

1. Obstetrics and Gynecology Unit, Ospedale Santa Maria Annunziata, USL Toscana Centro, Bagno a Ripoli, 50012 Firenze, Italy

2. Clinic of Obstetrics and Gynecology, S. Maria della Misericordia University Hospital, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), 33100 Udine, Italy

3. Medical Area Department (DAME), University of Udine, 33100 Udine, Italy

4. Obstetrics and Gynaecology Unit, Dipartimento Centro di Eccellenza Donna e Bambino Nascente, Fatebenefratelli Gemelli Isola Tiberina, 00168 Rome, Italy

5. Dipartimento per le Scienze Della Salute Della Donna, del Bambino e di Sanità Pubblica, UOC Ginecologia Oncologica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy

6. Pathology Unit, Department of Woman and Child’s Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy

7. Pathology Institute, Catholic University of Sacred Heart, 00168 Rome, Italy

Abstract

Extraskeletal Ewing sarcoma is a rare soft tissue tumor primarily affecting pediatric patients. The treatment is currently based on a multidisciplinary approach which allows, in cases of localized disease, good survival rates. We report the case of a 15-year-old female patient with a rapidly growing suspected pelvic mass misdiagnosed following the preliminary radiological exams, which assessed the findings as a mass of ovarian origin. The girl underwent surgery and, thanks to histopathological, immunohistochemical and real-time polymerase chain reaction (RT-PCR) examinations, it was possible to make the right diagnosis and to administer the best treatment in terms of surgery, chemotherapy and radiotherapy, obtaining a long disease-free interval and no recurrence to date.

Publisher

MDPI AG

Subject

Health Information Management,Health Informatics,Health Policy,Leadership and Management

Link

https://www.mdpi.com/2227-9032/11/10/1373/pdf

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