Affiliation:
1. Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia
2. Pharmacology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt
Abstract
Acute coronary syndrome (ACS) is a leading cause of cardiovascular-related morbidity and mortality worldwide. The present study investigated the health-related quality of life (HRQOL) and drug prescribing patterns in ACS patients at Riyadh hospitals in Saudi Arabia. This study was a 12-month prospective cross-sectional study that included 356 patients with ACS. The current study showed that younger male (67.42%) and urban (75.84%) patients suffered more from ACS. Moreover, most patients with NSTEMI (51.69%) experienced Grade 1 dyspnea (33.43%) and NYHA Stage 2 (29.80%); however, STEMI patients were at greater mortality risk. The HRQOL questionnaire showed that ACS patients were significantly impaired in all QOL domains (emotional [23.0%, p = 0.001], physical [24.4%, p = 0.003], and social [27.2%, p = 0.002]). Furthermore, the most commonly prescribed medications were statins (93%), antiplatelets (84%), anticoagulants (79%), coronary vasodilators (65%), and beta-blockers (63%). Additionally, 64% of patients received PCIs or CABGs, with the majority of cases receiving PCIs (49%), whereas 9% received dual anticoagulant therapy. Thus, there is an urgent need to educate healthcare teams about the relevance of QOL in ACS control and prevention and the new ACS management recommendations. ACS is also growing among younger people, requiring greater attention and prevention.
Funder
Deputyship for Research & Innovation, Ministry of Education
Subject
Health Information Management,Health Informatics,Health Policy,Leadership and Management
Reference53 articles.
1. Wacker-Gussmann, A., and Oberhoffer-Fritz, R. (2022). Cardiovascular risk factors in childhood and adolescence. J. Clin. Med., 11.
2. Epidemiology of coronary heart disease and acute coronary syndrome;Leischik;Ann. Transl. Med.,2016
3. World Health Organization (2014). Global Status Report on Noncommunicable Diseases 2014, World Health Organization.
4. Heart disease and stroke statistics—2023 update: A report from the American Heart Association;Tsao;Circulation,2023
5. Prescription Pattern and Drug Utilization Analysis in Patients with Acute Coronary Syndrome;Saju;Indian J. Pharm. Pract.,2020