Exploring the Frontier of 3D Bioprinting for Tendon Regeneration: A Review

Author:

Rosset Josée1,Olaniyanu Emmanuel1,Stein Kevin1,Almeida Nátaly Domingues23ORCID,França Rodrigo12ORCID

Affiliation:

1. Department of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 5V6, Canada

2. Department of Restorative-Dentistry, College of Dentistry, University of Manitoba, Winnipeg, MB R3E 0W2, Canada

3. Department of Diagnosis and Surgery, University of the State of São Paulo, São José dos Campos 12245-000, SP, Brazil

Abstract

The technology of 3D bioprinting has sparked interest in improving tendon repair and regeneration, promoting quality of life. To perform this procedure, surgical intervention is often necessary to restore functional capacity. In this way, 3D bioprinting offers a scaffold design, producing tendons with precise microarchitectures, promoting the growth of new tissues. Furthermore, it may incorporate bioactive compounds that can further stimulate repair. This review elucidates how 3D bioprinting holds promise for tendon repair and regeneration, detailing the steps involved and the various approaches employed. They demonstrate future challenges and perspectives and provide valuable information on the concept, bioprinting design, and 3D bioprinting techniques for the repair of tendon injuries.

Publisher

MDPI AG

Reference36 articles.

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4. Nordin, M., and Frankel, V.H. (2012). Basic Biomechanics of the Musculoskeletal System. Lippincott Williams & Wilkins. [4th ed.].

5. Spontaneous tendon ruptures. Etiology, pathogenesis and therapy;Resch;Orthopade,1995

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