Comparison of the Results of Cardiopulmonary Exercise Testing between Healthy Peers and Pediatric Patients with Different Echocardiographic Severity of Mitral Valve Prolapse

Author:

Huang Ming-Hsuan1,Tuan Sheng-Hui23ORCID,Tsai Yun-Jeng4,Huang Wei-Chun56,Huang Ta-Cheng7,Chang Shin-Tsu18,Lin Ko-Long16910

Affiliation:

1. Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, No. 386, Ta-Chung 1st Road, Kaohsiung 81362, Taiwan

2. Department of Rehabilitation Medicine, Cishan Hospital, Ministry of Health and Welfare, Kaohsiung 842, Taiwan

3. Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan

4. Jia Huan Rehabilitation Clinic, Kaohsiung 830, Taiwan

5. Department of Critical Care Medicine and Cardiology Center, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan

6. School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan

7. Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan

8. School of Medicine, National Defense Medical Center, Taipei 11490, Taiwan

9. School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan

10. Department of Post-Baccalaureate Medicine, National Sun Yat-sen University, Kaohsiung 804, Taiwan

Abstract

Patients with mitral valve prolapse (MVP) have been reported to have exercise intolerance. However, the underlying pathophysiological mechanisms and their physical fitness remain unclear. We aimed to determine the exercise capacity of patients with MVP through the cardiopulmonary exercise test (CPET). We retrospectively collected the data of 45 patients with a diagnosis of MVP. Their CPET and echocardiogram results were compared with 76 healthy individuals as primary outcomes. No significant differences regarding the patient’s baseline characteristics and echocardiographic data were found between the two groups, except for the lower body mass index (BMI) of the MVP group. Patients in the MVP group demonstrated a similar peak metabolic equivalent (MET), but a significantly lower peak rate pressure product (PRPP) (p = 0.048). Patients with MVP possessed similar exercise capacity to healthy individuals. The reduced PRPP may indicate compromised coronary perfusion and subtle left ventricular function impairment.

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference56 articles.

1. Mitral Valve Prolapse, Ventricular Arrhythmias, and Sudden Death;Basso;Circulation,2019

2. Prevalence of mitral valve prolapse in ethnic groups;Theal;Can. J. Cardiol.,2004

3. Mitral valve prolapse;Althunayyan;Expert Rev. Cardiovasc. Ther.,2019

4. Mitral valve prolapse in the general population. 1. Epidemiologic features: The Framingham Study;Savage;Am. Heart J.,1983

5. Common Phenotype in Patients With Mitral Valve Prolapse Who Experienced Sudden Cardiac Death;Hourdain;Circulation,2018

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

全球学者库

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2023 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3