1. National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy
2. Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, 00161 Rome, Italy
3. Core Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy
4. Department of Cardiovascular, Endocrine-Metabolic Diseases and Ageing, Istituto Superiore di Sanità, 00161 Rome, Italy