Unraveling Immunological Dynamics: HPV Infection in Women—Insights from Pregnancy-Reference-Cited by-同舟云学术

Unraveling Immunological Dynamics: HPV Infection in Women—Insights from Pregnancy

Published:2023-09-27 Issue:10 Volume:15 Page:2011
ISSN:1999-4915
Container-title:Viruses
language:en
Short-container-title:Viruses

Author:

Condrat Carmen Elena¹,Cretoiu Dragos²³^ORCID,Radoi Viorica Elena²³,Mihele Dana Mihaela⁴⁵,Tovaru Mihaela⁴⁵,Bordea Cristian Ioan⁶^ORCID,Voinea Silviu Cristian⁶,Suciu Nicolae¹³⁷

Affiliation:

1. Department of Obstetrics and Gynecology, Polizu Clinical Hospital, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania

2. Department of Genetics, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania

3. Fetal Medicine Excellence Research Center, Alessandrescu-Rusescu National Institute for Mother and Child Health, 020395 Bucharest, Romania

4. Department of Dermatology, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania

5. Dermatology Department, Victor Babes Clinical Hospital of Infectious and Tropical Diseases, 030303 Bucharest, Romania

6. Department of Surgical Oncology, Prof. Dr. Alexandru Trestioreanu Oncology Institute, Carol Davila University of Medicine and Pharmacy, 252 Fundeni Rd., 022328 Bucharest, Romania

7. Department of Obstetrics and Gynecology, Polizu Clinical Hospital, Alessandrescu-Rusescu National Institute for Mother and Child Health, 020395 Bucharest, Romania

Abstract

During pregnancy, hormonal and immune adaptations are vital for supporting the genetically distinct fetus during elevated infection risks. The global prevalence of HPV necessitates its consideration during pregnancy. Despite a seemingly mild immune response, historical gestational viral infections underscore its significance. Acknowledging the established HPV infection risks during pregnancy, our review explores the unfolding immunological changes in pregnant women with HPV. Our analysis aims to uncover strategies for safely modulating the immune system, mitigating adverse pregnancy consequences, and enhancing maternal and child health. This comprehensive narrative review delves into the existing knowledge and studies on this topic.

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

Link

https://www.mdpi.com/1999-4915/15/10/2011/pdf

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