Fluorescent-Nanoparticle-Impregnated Nanocomposite Polymeric Gels for Biosensing and Drug Delivery Applications

Author:

Gandla Kumaraswamy1ORCID,Kumar K. Praveen2ORCID,Rajasulochana P.3,Charde Manoj Shrawan4,Rana Ritesh5ORCID,Singh Laliteshwar Pratap6ORCID,Haque M. Akiful7ORCID,Bakshi Vasudha8ORCID,Siddiqui Falak A.910,Khan Sharuk L.910ORCID,Ganguly S.11

Affiliation:

1. Department of Pharmaceutical Analysis, Chaitanya (Deemed to be University), Hyderabad 500075, India

2. Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Government of NCT of Delhi, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi 110017, India

3. Department of Microbiology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Kanchipuram 602105, India

4. Department of Pharmaceutical Chemistry, Government College of Pharmacy, Karad 415124, India

5. Department of Pharmaceutics, Himachal Institute of Pharmaceutical Education and Research (HIPER), Hamirpur 177033, India

6. Department of Pharmaceutical Chemistry, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Rohtas 821305, India

7. Department of Pharmaceutical Analysis, School of Pharmacy, Anurag University, Hyderabad 500088, India

8. Department of Pharmaceutics, School of Pharmacy, Anurag University, Hyderabad 500088, India

9. Department of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, India

10. Department of Pharmaceutical Chemistry, School of Pharmacy, Anurag University, Hyderabad 500088, India

11. Bar-Ilan Institute for Nanotechnology and Advanced Materials, Ramat Gan 5290002, Israel

Abstract

Nanocomposite polymeric gels infused with fluorescent nanoparticles have surfaced as a propitious category of substances for biomedical purposes owing to their exceptional characteristics. The aforementioned materials possess a blend of desirable characteristics, including biocompatibility, biodegradability, drug encapsulation, controlled release capabilities, and optical properties that are conducive to imaging and tracking. This paper presents a comprehensive analysis of the synthesis and characterization of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels, as well as their biomedical applications, such as drug delivery, imaging, and tissue engineering. In this discourse, we deliberate upon the merits and obstacles linked to these substances, encompassing biocompatibility, drug encapsulation, optical characteristics, and scalability. The present study aims to provide an overall evaluation of the potential of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels for biomedical applications. Additionally, emerging trends and future directions for research in this area are highlighted.

Publisher

MDPI AG

Subject

Polymers and Plastics,Organic Chemistry,Biomaterials,Bioengineering

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Bioresorbable polymer-based sensors for medical applications;Bioresorbable Polymers and their Composites;2024

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