Targeted Covalent Inhibitors in Drug Discovery, Chemical Biology and Beyond-Reference-Cited by-同舟云学术

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Targeted Covalent Inhibitors in Drug Discovery, Chemical Biology and Beyond

Published:2024-02-05 Issue:2 Volume:17 Page:206
ISSN:1424-8247
Container-title:Pharmaceuticals
language:en
Short-container-title:Pharmaceuticals

Author:

Serafim Ricardo A. M.¹,Gehringer Matthias¹²^ORCID,Borsari Chiara³^ORCID

Affiliation:

1. Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls University Tübingen, 72076 Tübingen, Germany

2. Cluster of Excellence iFIT (EXC 2180) ‘Image-Guided & Functionally Instructed Tumor Therapies’, University of Tübingen, 72076 Tübingen, Germany

3. Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy

Abstract

Covalent inhibitors have experienced a revival in medicinal chemistry and chemical biology in recent decades [...]

Publisher

MDPI AG

Link

https://www.mdpi.com/1424-8247/17/2/206/pdf

Reference20 articles.

1. Advances in covalent drug discovery;Boike;Nat. Rev. Drug Discov.,2022

2. The Ascension of Targeted Covalent Inhibitors;Singh;J. Med. Chem.,2022

3. Targeted Covalent Inhibitors for Drug Design;Baillie;Angew. Chem. Int. Ed. Engl.,2016

4. Covalent inhibitors in drug discovery: From accidental discoveries to avoided liabilities and designed therapies;Bauer;Drug Discov. Today,2015

5. The resurgence of covalent drugs;Singh;Nat. Rev. Drug Discov.,2011

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