Progress in PRRSV Infection and Adaptive Immune Response Mechanisms

Author:

Cai Huanchang1,Zhang Hewei23,Cheng Huai1,Liu Min1,Wen Shubo4,Ren Jingqiang13ORCID

Affiliation:

1. Wenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China

2. College of Food and Drugs, Luoyang Polytechnic, Luoyang 471099, China

3. Animal Diseases and Public Health Engineering Research Center of Henan Province, Luoyang 471000, China

4. Preventive Veterinary Laboratory, College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China

Abstract

Since its discovery, Porcine reproductive and respiratory syndrome (PRRS) has had a huge impact on the farming industry. The virus that causes PRRS is Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and because of its genetic diversity and the complexity of the immune response, the eradication of PRRS has been a challenge. To provide scientific references for PRRSV control and vaccine development, this study describes the processes of PRRSV-induced infection and escape, as well as the host adaptive immune response to PRRSV. It also discusses the relationship between PRRSV and the adaptive immune response.

Funder

Youth Growth Technology Project of Jilin Provincial Science and Technology Development Program

Core Technical Public Welfare Project of Luoyang, China

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

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