Oxygen Deficient (OD) Combustion and Metabolism: Allometric Laws of Organs and Kleiber’s Law from OD Metabolism?

Author:

Annamalai Kalyan

Abstract

The biology literature presents allometric relations for the specific metabolic rate (SMRk) of an organ k of mass mk within the body of mass mB: SMRk ∝ mBfk (body mass allometry, BMA). Wang et al. used BMA, summed-up energy from all organs and validated Kleiber’s law of the whole body: SMRM ∝ mBb’, b’ = −0.25. The issues raised in biology are: (i) why fk and b’ < 0, (ii) how do the organs adjust fk to yield b’? The current paper presents a “system” approach involving the field of oxygen deficient combustion (ODC) of a cloud of carbon particles and oxygen deficient metabolism (ODM), and provides partial answers by treating each vital organ as a cell cloud. The methodology yields the following: (i) a dimensionless “group” number GOD to indicate extent of ODM, (ii) SMRk of an organ in terms of the effectiveness factor; (iii) curve fitting of the effectiveness factor to yield the allometric exponents for the organ mass-based allometric laws (OMA); (iv) validation of the results with data from 111 biological species (BS) with mB ranging from 0.0075 to 6500 kg. The “hypoxic” condition at organ level, particularly for COVID-19 patients, and the onset of cancer and virus multiplication are interpreted in terms of ODM and glycolysis.

Publisher

MDPI AG

Subject

Information Systems and Management,Computer Networks and Communications,Modeling and Simulation,Control and Systems Engineering,Software

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